Genetic linkage mapping for a large number of families identifies 4% recombinati

Question

Genetic linkage mapping for a large number of families identifies 4% recombination between the genes for { m Rh} blood type and elliptocytosis. At the { m Rh} locus, alleles R and r control { m Rh}+ and { m Rh}- blood types. Allele E producing elliptocytosis is dominant to the wild-type recessive allele e. Tom and Terri each have elliptocytosis, and each is { m Rh}+. Tom's mother has elliptocytosis and is { m Rh}- while his father is healthy and has { m Rh}+. Terri's father is { m Rh}+ and has elliptocytosis; Terri's mother is { m Rh}- and is healthy.

What is the probability that the first child of Tom and Terri will be Rh- and have elliptocytosis?

What is the probability that a child of Tom and Terri who is Rh+ will have elliptocytosis?

Explanation / Answer

The answer to the second question is 0.679.

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