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Chloramphenicol is an antibiotic that targets prokaryotic (70S) ribosomes, but n

ID: 25297 • Letter: C

Question

Chloramphenicol is an antibiotic that targets prokaryotic (70S) ribosomes, but not eukaryotic (80S) ribosomes. Which of these questions stems from this observation, plus an understanding of eukaryotic origins? a. How is translation affected in ribosomes that are targeted by chloramphenicol? b. Can chloramphenicol also be used to control human diseases that are caused by archaeans? c. If chloramphenicol inhibits prokaryotic ribosomes, should it not also inhibit mitochondrial ribosomes? d. Can chloramphenicol pass through the capsules possessed by many cyanobacteria? e. Why aren't prokaryotic ribosomes identical to eukaryotic ribosomes?

Explanation / Answer

c. If chloramphenicol inhibits prokaryotic ribosomes, should it not also inhibit mitochondrial ribosomes

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