a. Why are two numbers shown for each individual? (the \"fractions\" below each
ID: 253912 • Letter: A
Question
a. Why are two numbers shown for each individual? (the "fractions" below each individual and the numbers above each invidicual)
b. What do you think is the relationship between the number of repeats and whether the disease is present at birth (congenitalon set, shown in red)?
(white circle says sublinical symptoms, gray below that one says adult onset, the other grey one says juvenile onset, and the red one says congenital onset. THANKS!)
Famdly with Myotanic Dystrophy 2 3 69 5/13 2 /M B 6/76 14/16 13/aa 2 3 6 14/14113/11213/ 5/16g15/24 16/20 14/100Explanation / Answer
a. The fraction indicates the ratio of length of GCT repeats and the length tested. The number above the individual indicates the position of that particular individual in a particular generation which is denoted by Roman numericals (Indicated on the left side).
b. From the pedigree we can interpret the following:
From, the interpretations, we can say that the disease is autosomal dominant disease.
Additionally, we can say that the age at which the symptoms appear is indicated by the number of repeats. As the number of repeats increases, the age at which the symptoms appear decreases.
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