3. Indicate by Yes or No whether the protein content of the following structures

Question

3. Indicate by Yes or No whether the protein content of the following structures will be directly affected by a defect in the ER protein trafficking pathway. (0.2 points each) a. The plasma membrane (PM); b. The peroxisome; c. The mitochondrion; d. The chloroplast; e. Transport vesicles; f. The Golgi network; g. The cytosol; h. The ER: The endosomes; j. The lysosomes; k. The transition vesicles; I. The endocytic vesicles. 4. Which compartment of the Golgi network accomplishes the following? (0.25 points each) a. Proteins processing (modification): b. Sending of material to the PM and endosomes: c. Reception of material from the ER d. Sorting of proteins by final destination: Proteins are modified as they travel within the ER and Golgi networks, where does each of the following processes specifically take place? (0.2 points each) 5. a. Attachment of N-acetylglucosamine; b. Biosynthesis of core oligosaccharide; c. Phosphorylation of lysosomal proteins; d. Attachment of sulfate to tyrosine; e. Removal of misfolded proteins;

Explanation / Answer

Answer 3. a. The plasma membrane = yes

B. The peroxisome = no

C the mitochondria = no

D the chloroplasts = no

E. Transport vesicles = yes

F. The Golgi network =yes

G the cytosol = no

H. The ER = yes

I. The endosomes = yes

J the lysosomes = yes

K. The transition vesicles = yes

L the endocytic vesicles = no

Answer 4. A protein processing (modification)= in cis, medial and trans part of Golgi apparatus.

B. Sending of material to PM and endosomes = trans Golgi network

C. Reception of material from ER. = cis Golgi network

D.sorting of protein by final destination = trans Golgi network

Answer 5 A.) Attachment of N- acetylglucosamine = Cis Golgi network

B.) Biosynthesis of core oligosaccharide = ER

C) phosphorylation of lysosomal protein. = medial Golgi cisternae.

D) attachment of sulfate to tyrosine = Trans Golgi network

E) removal of misfolded protein = ER

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