Can be multiple! Thank you Question 7 2 pts Which of the following are true in r

Question

Can be multiple! Thank you

Question 7 2 pts Which of the following are true in regard to Ca2+ in the cell? O The large gradient tending to drive Ca2+ into the cytosol from both the ER and plasma membranes leads to Ca2+ rushing into the cytosol when Ca2+ channels are activated Increased local Ca2+ opens nearby IP3 and Ryanodine receptors by calcium-induced calcium release. Calcium ATPases in the plasma membrane and ER help to maintain low levels of calcium in the cytosol. Ca2+ directly activates PKA by releasing it from inhibitory subunits The frequency of Ca2+ oscillation can code a specific cellular response.

Explanation / Answer

1) Incorrect. The large gradient tending to drive Ca2+ into the cytosol from plasma membrane leads to Ca2+ rush into the cytosol when Ca2+ channels are activated into the plasma membrane upon ligand binding.

2) Correct. Increased local Ca2+ opens nearby IP3 and Ryanodine receptors into the ER.

3) Correct. Calcium ATPases in the plasma membrane and ER help ti maintain low levels of calcium into the cyosol.

4) Incorrect. Ca2+ indirectly activates PKA via cAMP response.

5) Correct. The frequency of Ca2+ oscillation codes a specific cellular response.

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