Growth fractions for two different types of tumors originating from epilthelial
ID: 258472 • Letter: G
Question
Growth fractions for two different types of tumors originating from epilthelial and embryonic cells were analyzed. The epithelial tumor growth factor of 75% while it was 50% for the embryonic tumor. The proliferation (P) and the quiescent (Q) for the two types of the cells are indicatted by P1/P2 and Q1/Q2, respectively. What is the relation between P and Q in this case?
a. Calculate P1/Q1 and P2/Q2 from the above given growth fractions.
b. If Q1 and Q2 are the same, then evaluate which of the two tumors has a higher proliferation?
*** EQUATION ***
Growth fraction (GF) = P / (P + Q)
There is no more information given, but let's assume that Q = 1000
Explanation / Answer
A. P1 = 75
q1 = 25
p1/q1 = 75/25 = 3
P2 = 50
q2 = 50
p2/q2 = 50/50 = 1
B. Q = 1000
P1 = 75% = 750
GF = 750/750+1000 = 750/1750 = 0.42
P2 = 50% = 500
GF = 500 / 500+1000 = 500/1500 = 0.33
epithelial tumor growth has high proliferation.
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