Item 3 3 of 3 Review the Figure for the wild-lype expression of the eve stripes.

Question

Item 3 3 of 3 Review the Figure for the wild-lype expression of the eve stripes. FIGURE gene in the developing embryo. (a) evex pression pattern in the early embryo. (b) The eve locus contains more than 12 kbof regu- latory DNA The 5 regulatory region con- tains two enhancers, which control the expression of stripes 2, 3, and 7. Each en- harcer is 500 bp in length. The 3 regulatory region contains three enhancers thatcontrol the expression of stripes 4 and 6, stripe 1, and stripe 5, respectively. Thefive enhancers produce seven stripes of eve expression in the early embryo. (a Image courtesy of Michael Levine.) Expression of the eve stripe #3. #7 enhancer stripe #2 enhancer stripe #4?#6 enhancer stripe #1, #5 enhancer cod 4 kb3 1 +1+2 3 4 +5 67 8 Part A If the enhancer for eve stripes #3 and #7 in the 5 regulatory region of the eve gene is deleted, predict the pattern of eve stripes in the embryo. O O O O The eve stripes #2, #3, and 17 would be missing, and stripes #1, #4, #5, and 6 would form like normal The eve stripes #3 and #7 would be missing, and stripes #1, #2, #4. #5, and #6 would form like normal The eve stripes #1, #2, #4, t5, and #6 would be missing, and stripes #3 and #7 would form like normal The eve stripes #1, #4, #5, and #6 would be missing, and stripes #2, #3, and #7 would tomm like normal

Explanation / Answer

Second option is the correct answer.

If only enhancers for stripe #3 and #7 are deleted, the expression of genes which code for stripe #3 & #7 will only be affected. Other genes would be expressed normally.

An enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription of a particular gene will occur.

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