The Ras protein is a GTPase that functions in many growth-factor signaling pathw

Question

The Ras protein is a GTPase that functions in many growth-factor signaling pathways. In its active form, with GTP bound, it transmits a downstream signal that leads to cell proliferation; in its inactive form, with GDP bound, the signal is not transmitted. Mutations in the gener for Ras arefound in many cancers. of the choices below, which alteration of Ras activity is most likely to contribute to the uncontrolled growth of cancer cells? a.a change that prevents Ras from being made b. a change that increased the affinity of Ras for GDP c. a change that decreases the affiniity of Ras for GTP d. a change that decreases the rate of hydrolysis of GTP by Ras

Explanation / Answer

A change that decreases the rate of hydrolysis of GTP by Ras

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