1. What is meant by a neutral polymorphism? a) a change in DNA that changes a mu
ID: 261550 • Letter: 1
Question
1. What is meant by a neutral polymorphism?
a) a change in DNA that changes a mutation back to wild type?
b) a difference in DNA sequence that changes a charged amino acid to a neutral amino acid
c) a difference in DNA sequence that has no physiological effect
2. What is the significance of this table in the context of examining a family or population for BRCA1 mutations that predispose an individual to cancer?
a)Such neutral polymorphisms make screening difficult in that one cannot always be certain that a mutation will cause problems for the patient.
b) Such neutral polymorphisms make screening easy in that one can always be certain if a mutation will cause problems for the patient.
Explanation / Answer
ANSWER 1.
A neutral polymorphism means:
c) A difference in DNA sequence that has no physiological effect.
ANSWER 2.
The significance of this table in the context of examining a family or population for BRCA1 mutations that predispose an individual to cancer:
a) Such neutral polymorphisms make screening difficult in that one cannot always be certain that a mutation will cause problems for the patient.
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