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Suppose that a nucleic acid polymer consisting of 50% U and 50% C in randomly or

ID: 262753 • Letter: S

Question

Suppose that a nucleic acid polymer consisting of 50% U and 50% C in randomly order is used as a template for protein synthesis in a cell-free system. Using the Table below pick the 4- 8 amino acids encoded by the resulting codons and choose the corresponding probability (frequency) that each of these amino acids would be incorporated into the corresponding polypeptide. The final TOTAL probability/frequency for the incorporation of the specified amino acid must add up to 100% Frequency lanine inine 12.5% 25% 375% 50% 62.5% 75% 87.5% 100% spartate sparagine steine lutamate Glutamine lycine Histidine Isoleucine Leucine Lysine Methionine Phenylalanine Proline erine reronine ryptophan Tyrosine Valine TOTAL 100% Submit Answer Tries 0/99

Explanation / Answer

Codons resulting are as follows:

UUU - codes for phenylalanine amino acid

UUC - codes for phenyl alanine amino acid

UCU - codes for serine amino acid

UCC - codes for serine amino acid

CCC - codes for proline amino acid

CCU - codes for proline amino acid

CUC - codes for leucine amino acid

CUU - codes for leucine amino acid

The probability of incorporation of each amino acid in the polypeptide chain is 12.5%. Each amino acid is encoded by two different codons. So, the probability of the 4 encoded amino acids to be incorporated into the polypeptide chain is 2 x 12.5% = 25%.

So, the probability of incorporation of phenylalanine is 25%, serine is 25%, proline is 25% and leucine is 25%.

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