The antibiotic gramicidin (pictured at right) is a channel protein that allows f

Question

The antibiotic gramicidin (pictured at right) is a channel protein that allows free passage of all ions across the bacterial cell membrane in whichever direction is down the ion's electrochemical gradient (indicated by arrows in both directions). In the lab you treat animal cells with gramicidin, where it is incorporated into the inner mitochondrial membrane. You find that the cells can no longer make ATP by oxidative phosphorylation even though the electron transport chain remains functional. a) Explain how incorporation of gramicidin into the mitochondrial membrane would prevent ATP synthesis by oxidative phosphorylation. (2-3 sentences, 3 pts.) b) Name two stages of respiration in these animal ells that could continue to produce small amounts of ATP in the presence of gramicidin. (2 pts)

Explanation / Answer

The antibiotic gramicidin (pictured at right) is a channel protein that allows f

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