Which description is correct for CD4+ T-cell activation in a draining lymph node

Question

Which description is correct for CD4+ T-cell activation in a draining lymph node?

a. After they have been activated, they require signal 1, signal 2 and signal 3 for their effector function.

b. An individual cell can acquire different functions depending on the type of infection the dendritic cell reports.

c. All activated CD4+ T-cells must exit the lymph node to provide their helper function.

d. If their function is to help macrophages fighting a local infection, they “swim” against the lymph flow to get there right away (use of the afferent lymphatic duct).

Explanation / Answer

A. After they have been activated, they require signal 1, signal 2 and signal 3 for their effector function.

Lymphocytes wind up enacted when they are presented by peptide antigens MHC class II, which are communicated on the surface of antigen-presenting cells (APCs). Once enacted, they partition quickly and emit little proteins called cytokines that control or aid the dynamic invulnerable reaction.

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