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Slide Show Review Insert EText Picture Shape Media Arrange Quick Styles Play Three months after a needle-stick exposure to blood from a patient with hepatitis B, a nurse is evaluated for infection with the virus. Laboratory results reveal: HBsAg: negative Anti-HBs antibody: negative IgM anti-HBc: positive lgG anti-HBc: negative HBeAg: negative On the basis of these results, which of the following most accurately describes the nurse's hepatitis B status? A. She had been effectively vaccinated against hepatitis B before the needle-stick exposure occurred. B. She has mounted an inappropriate antibody response to hepatitis B as a result of an immunocompromised state. C. She is a carrier of hepatitis B D. She is actively infected with hepatitis B E. She was not infected with hepatitis B. Side 66 of 93

Explanation / Answer

Hepatitis B is a serious liver infection that can be prevented by vaccination.

When infected with hepatitis B core antigen, the first antibody produced is IgM upto 6 months.

A positive IgM anti-HBc test indicates previous or ongoing infection with Hepatitis B. Presence of IgM anti-HBc indicates acute infection.

A postitive IgG anti-HBc test indicates patients who have recovered from hepatitis B or those who have chronic HBV infection.

Thus, the correct option is D).

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