7) Pathogen (parasite) response of invertebrates? associated molecular patterns,

Question

7) Pathogen (parasite) response of invertebrates? associated molecular patterns, PAMPs, play what role in the immune a) PAMPs are found on the surface of hemocytes, and have contact capabilities b) PAMPs -dependent cytolyi are cytokines that are released when invertebrate cells are invaded are damaged by a c) PAMPs are the pathogen-encoded triggers of inducible innate immune responses d) none of the above 8) Which parasitic infection results in cardiomyooyte hypertrophy as part of disease pethology Chagas disease (T. cua) b) Malaria (Plasmodlium) c) Sleeping sickness (T. bruce) d) Trichinellosis (T. spiralis) 9) Antibodies are a key component of antiplasmodium and antimalarial immune responses. Which of the following is an immune evasion strategy used by Plasmodium falciparum parasites to overcome this? a) antigenic variation c) both of the above d) neither of the above mammals: 10) Which of the following is an antiparasitic effector mechanism ot a) complement mediated lysis b) cytotoxic T cell mediated lysis c) respiratory burst by activated macrophages d) all of the above 11) The chronic pathology of schistosomiasis is largely due to: A- Seizures due to death of cercarlae in the brain B- Feeding behavior of adult schistosomes C- Eggs trapped in tissues D- Migration of larvae into the bile ducts 12) Which of the following best characterizes the relationship between (parasitic) infection and parasitic) disease? a) all people who are infected have disease b) all people who have are infected will eventually develop disease c) all people who are infected may develop (clinical) disease d) disease is determined by host factors, so should be considered independent of infection 13) Which of the following statements is true: a) Parasites are typicall incapable of blunting the immune response of their hosts b) Degenerating parasites can provoke severe immune responses in the host c) both of the above d) neither of the above

Explanation / Answer

7.) c

Explaination:Pathogen-associated molecular patterns, or PAMPs, are molecules associated with groups of pathogens, that are recognized by cells of the innate immune system. These molecules can be referred to as small molecular motifs conserved within a class of microbes.

8.a.

explaination:Chagas' disease, the leading cause of heart failure in Latin America, results from infection with the intracellular protozoan parasite Trypanosoma cruzi

9. a

explaination:

Antigenic variation and immune evasion in Plasmodium falciparum malaria

10 d

11 c

explaination:Chronic schistosomiasis. The pathology of chronic schistosomiasis, which is far more common than the acute form of the infection, results from egg-induced immune response, granuloma formation, and associated fibrotic changes. ... (Eggs may require an intense immune response to aid their migration through the body.)

12 d

13 b

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