mans have two sources of cholesterol: absorption from ingested food and de novo
ID: 270557 • Letter: M
Question
mans have two sources of cholesterol: absorption from ingested food and de novo synthesis by the liver. gh levels of cholesterol in the blood correlates with cardiovascular disease, but cholesterol is required to regulate membrane fluidity and as a precursor for important molecules like steroids and bile acids. Thus, humans evolved several types of regulation of cholesterol levels. the human body compensate for changes in he levels of cholesterol? (choose all that are correct) High amounts of ATP result in phosphorylation of HMG CoA reductase to inactivate its activity. High cholesterol levels inhibit transcription and production of the LDL receptor A drop in cholesterol levels activates transcription of HMG CoA reductase using the transcription factor SREBP2. Adecrease inthe number of LDL receptors results in more cholesterol uptake into cells.Explanation / Answer
The correct answesr are (2) and (4).
High cholesterol levels inhibit transcription and production of the LDL receptor.
A decrease in the number of LDL receptors results in more cholesterol uptake into cells.
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