My Antifungal Drug for my paper is “Terbinafine Hydrochloride” - I’m needing to

Question

My Antifungal Drug for my paper is “Terbinafine Hydrochloride” - I’m needing to know what the Composition is. (Above is ONLY an example of what the teacher expects)
Possible Additional Extra Credit (percentage commensurate with extent of research) As each topic will include a method of prevention and treatment, you will be allowed to submit a 1-page report summarizing the antimicrobials utilized to treat the pathogeneses relevant to your topic. An example of the material required to provide tor an Antimicrobial Mode of Category Composition Spectrum Common Usage Limitations and Erythromycin inhibtion Ani-Cactenial large macrocycic Narow, similar used in the treatment o Prlonged used of individual antimicrobial is below Side Effects Drug nhitbition actone ring to to penicillin, andrespiratory tract medication can cause overgrowth of non- of proteln one o moreprescribedtae infections (upper and tower), pertussis is often deoxy sugars are prescibed to susceptible bacteria or Bacterlostaticattached. patents that are (whooping cough) and tungt. This product contains allergic to Legionnaires diseasesucrose. Patlents with penicilin caused by Legionellaructose intolerance, alactose diseaseructose lacse Bactéricidal pneumophila and several other Infections malabsorption or sucrase Route: per ora-Adults Isomaltase Insufficiency and elderly 250mg 6 should not take this medicine hrs. 500mg o 12hrs may b given it desired. Do not exceed 1gram. st1

Explanation / Answer

Terbinafine Hydrochloride : It is the anti fungal medication used to treat ring worm, fungal nail(Finger nail, toe nail) infection, tinea versicolor. Chemical formula of the drug is C21H25N•HCl.

it is a white fine crystalline powder that is freely soluble in methanol and dichloromethane, soluble in ethanol, and less soluble in water also. it may accumulate in hair, nail,skin as it is hydrophobic in nature.

It inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that catalyzes the conversion of squalene to lanosterol. Lanosterol is then converted to ergosterol In fungi ; lanosterol becomes cholesterol in humans.

Terbinafine thought to inhibit ergosterol production in fungi without significantly affecting cholesterol production in humans. So, it is believed to change cell membrane permeability, causing fungal cell break downs.

SIDE EFFECT:

Common side effects may include:

diarrhea, nausea, gas, stomach pain or upset

rash

headache

abnormal liver function tests

USAGE:-

Terbinafine Dosage

Take terbinafine exactly as prescribed by your doctor.

Fingernail Fungus Infection - 250 mg once daily for six weeks

Toenail Fungus Infection - 250 mg once daily for 12 weeks

LIMITATION

This drug should not be used in case of

Related Questions

Navigate

• Browse (All)
• Browse M
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.