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1) A virus generally first encounters a potential host cell primarily by means o

ID: 274025 • Letter: 1

Question

1) A virus generally first encounters a potential host cell primarily by means of interactions with one or the other of which two of the following? Note: points will be deducted for wrong answers.

The endoplasmic reticulum

Cell surface receptors

The phospholipid head groups of the plasma membrane

Attachment factors such as glycans

The clathrin-coated pit

The nuclear membrane

The nuclear pore complex

The endosome

2) Which one or more of the following statements is/are true about viral attachment factors and receptors?  Note: points will be deducted for wrong answers.

Glycoproteins are the only components of viruses that can interact with attachment factors and receptors

Binding of attachment factors is usually irreversible, whereas receptor binding is usually reversible

Receptor binding is more specific than attachment factor binding

Receptor binding actively promotes viral penetration, whereas attachment factor binding does not

Some viruses bind to two or more cell surface receptors to initiate the viral entry process.

a.

The endoplasmic reticulum

b.

Cell surface receptors

c.

The phospholipid head groups of the plasma membrane

d.

Attachment factors such as glycans

e.

The clathrin-coated pit

f.

The nuclear membrane

g.

The nuclear pore complex

h.

The endosome

2) Which one or more of the following statements is/are true about viral attachment factors and receptors?  Note: points will be deducted for wrong answers.

a.

Glycoproteins are the only components of viruses that can interact with attachment factors and receptors

b.

Binding of attachment factors is usually irreversible, whereas receptor binding is usually reversible

c.

Receptor binding is more specific than attachment factor binding

d.

Receptor binding actively promotes viral penetration, whereas attachment factor binding does not

e.

Some viruses bind to two or more cell surface receptors to initiate the viral entry process.

Explanation / Answer

A virus generally first encounters a potential host cell primarily by means of interactions with one or other of which two of the following?

Cell surface receptors and attachment factors such as glycan

Which one of the following statement is true about viral attachment factors and receptors?

Glycoproteins are the only components of viruses that can interact with attachment factors and receptors.