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1. when in the mitochondrial matrix, citrate is an ______ pathway regulator, and

ID: 274774 • Letter: 1

Question

1. when in the mitochondrial matrix, citrate is an ______ pathway regulator, and inhibits _____________.

A. inter-; succinate dehydrogenase B. intra-; succinate dehydrogenase C. inter & intra-; succinate dehydrogenase and Complex II D. inter & intra-; pyruvate dehydrogenase, succinate dehydrogenase, and Complex II E. inter & intra-; pyruvate dehydrogenase and succinate dehydrogenase

2. After citrate is exported by CIC, citrate will _______ the enzyme/s of _____, which is/are part of the glycolytic pathway.

A. activate; fructose-1,6-bisphophatase B. activate; PFK1 C. inhibit; phosphofructokinase-1 and pyruvate kinase D. inhibit; hexokinase, phosphofructokinase-1, and pyruvate kinase E. inhibit; hexokinase, phosphofructokinase-1, phosphofructokinase-2; and pyruvate kinase

Explanation / Answer

1.when in the mitochondrial matrix, citrate is an nter & intra pathway regulator, and inhibits succinate dehydrogenase and Complex II

2.After citrate is exported by CIC, citrate will inhibit the enzyme/s of hexokinase, phosphofructokinase-1, and pyruvate kinase which is/are part of the glycolytic pathway

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