1- Cytotoxic T cells recognize and kill host cells infected by viruses. They rec
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Question
1- Cytotoxic T cells recognize and kill host cells infected by viruses. They recognize these cells by the foreign antigen displayed on the host cell’s:
MHC I molecules
MHCII molecules
toll like receptors
2- Clonal selection:
can be caused by vaccinations
explains why the immune system responds stronger to a second infection than a first
results in antibody specificity following a bacterial infection
all of the above
3- Which of the following describes innate immunity?
It is a response to a specific pathogen and is the basis for the use of vaccines.
It is the basis for the use of vaccines.
It is a response to a specific pathogen.
It reacts to a wide variety of pathogens.
4- Specificity is a feature of which of the following?
neither the innate nor the adaptive immune systems
both the innate and adaptive immune systems
the adaptive immune system
the innate immune system
5- The complement system refers to:
proteins that are activated when histamine levels increase.
proteins circulating in the blood that are activated by antibodies or molecules on pathogens.
proteins circulating in the blood that are activated by opsonization.
proteins present on macrophages that recognize foreign proteins.
6- The adaptive immune system does NOT include:
B cells.
mast cells.
plasma cells.
memory cells.
T cells.
7- Genomic rearrangement in B cells occurs:
during clonal selection after antigen binding.
in the bone marrow when B cells divide and produce daughter B cells.
after clonal selection when antibodies are required for immune response.
in the gamete-producing cells of an individual.
8- Which of the following statements is/are TRUE regarding the secondary immune response? (Select all that apply.)
It occurs faster than the primary immune response.
It occurs more slowly than the primary immune response.
It produces fewer antibodies than the primary immune response.
It produces more antibodies than the primary immune response.
9- Sometimes an organ can be replaced by moving it from one part of the body to another. This can be done, for example, to replace damaged skin or joints. In these cases:
antigens would be generated against the transplanted organ.
antibodies would be generated against the transplanted organ.
immunosuppressant drugs would be required to prevent transplant rejection.
rejection of the transplanted organ would not be expected.
rejection of the transplanted organ would still be expected.
10- A woman goes to the doctor and is diagnosed with rheumatoid arthritis. What factors led to her developing this disease? (Select all that apply.)
Some of her T cells were not negatively selected.
Some of her T cells are recognizing and responding to herself antigens.
Some of her T cells were not positively selected.
Some of her T cells are not recognizing and associating with her MHC proteins.
11- Cells with class I MHC proteins that contain a foreign antigen will be destroyed after:
releasing histamine.
being bound by helper T cells.
stimulating the MAC.
being bound by cytotoxic T cells.
12- Virus-infected cells are detected and destroyed by which cell-mediated immune response?
macrophages
cytotoxic T cells
helper T cells
B cells
13- Which of the following is required to activate a helper T cell, which in turn can stimulate antibody production by B cells?
an antigen
a major histocompatibility complex
an antigen and a major histocompatibility complex protein
an antibody and a major histocompatibility complex protein
an antibody
14- The secretion of cytokines is a function of _____ cells.
plasma
cytotoxic T
killer T
helper T
Explanation / Answer
Ans 1 : MHC I molecules
The cytotoxic T cells recognise the specific antigens on the host cell which are bound to class I MHC molecules.
When the TCR is specific for that antigen , it binds to the complex of antigen and MHC molecule and destroys the cell.
These cells are called as CD8+ T cells.
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