Which protein facilitates the late phase of LTP Synaptotagmin PKC CaMKII CREB Y

Question

Which protein facilitates the late phase of LTP

Synaptotagmin

PKC

CaMKII

CREB

Y

ou are examining long-term potentiation in two groups of hippocampal neurons: control and treated. You induce lasting LTP in the control cells after repetitive high-frequency stimulation. In the treated cell, however, the potentiation begins to decrease after 2 hours. What treatment was given?

A drug that binds magnesium

A drug that inhibits protein synthesis

A drug that opens calcium channels

A drug that blocks sodium channels

The type of receptor that is critical for the induction of hippocampal LTP, admitting calcium into a dendritic spine, is called a(n)

NMDA receptor.

cholinergic GPCR

glycine receptor.

AMPA receptor.

Synaptotagmin

PKC

CaMKII

CREB

Explanation / Answer

1. CREB cAMP response element binding protein facilitates late phase of long term potentiation

3.NMDA receptor N.methyl Daspartate

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