(d) new DNA strands must be copied tro l low does the total number of replicatio
ID: 278049 • Letter: #
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(d) new DNA strands must be copied tro l low does the total number of replication origins in bacterial cells compare with the number of origins in human cells? (a) (b) (c) (d) 1 versus 100 5 versus 500 10 versus 1000 1 versus 10,000 Indicate whether the following statements are true or false F 3. Primase is needed to initiate DNA replication on both the leading strand and the lagging F 4. The sliding clamp is loaded once on each DNA strand, where it remains as strand. TF4. The sl replication is complete TFS. Telomerase is a DNA polymerase that carries its own RNA molecule to use as a primer at TF6. Primase requires a proofreading function that ensures there are no errors in the RNA prime 7. Sickle-cell anemia is an example of an inherited disease. Individuals with this disorder have misshapen end of the lagging strand. used for DNA replication. (sickle-shaped) red blood cells caused by a change in the sequence of the ß-globin gene. What is the nature of the change? (a) chromosome loss (b) base-pair change (c) gene duplication (d) base-pair insertion 8. RNA in cells differs from DNA in that it contains the base uracil, which pairs with cytosine it is single-stranded and cannot form base pairs (a) (it is single-stranded and can fold up into a variety of structures (d) the sugar ribose contains fewer oxygen atoms than does deoxyribose 43100.17075 6- SUBJECT I 150 SHEETS SUBJECT 150 SHEETS FIVE STARExplanation / Answer
2. Option D is correct.
There is a single ori in bacterial chromosome (Nucleoid). There are ~10000 Ori in eukaryotic chromosomes.
3. True
4. True
5. True
6. False. Primase does not exhibit proofreading function.
7. Option B is correct.
There is a Glu to Val change in the beta chain of Hb protein due to a base substitution.
8. Option C is correct.
RNA in cells is single-stranded. It folds into several secondary and tertiary conformations.
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