What causes the changes in protein structure through the three or four levels of

Question

What causes the changes in protein structure through the three or four levels of structure?

A. The primary chain forms secondary ?-helix and ?-pleated sheets which fold onto each other forming the tertiary structure.

B. The primary structure undergoes alternative splicing to form secondary structures, which fold on other protein chains to form tertiary structures.

C. The primary structure forms secondary ?-helix and ?-pleated sheets. This further undergoes phosphorylation and acetylation to form the tertiary structure.

D. The primary structure undergoes alternative splicing to form a secondary structure, and then disulfide bonds give way to tertiary structures.

Explanation / Answer

A. The primary chain forms secondary ?-helix and ?-pleated sheets which fold onto each other forming the tertiary structure.

Primary structure represents the linear sequence of amino acids that forms a protein. The primary structure folds into secondary structures which then fold onto each other to give tertiary structures. Primary structure thus determines the higher levels of a protein structure.

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