6. Which of the following is not required for protein transport into the mitocho

Question

6. Which of the following is not required for protein transport into the mitochondria? (a) signal sequence (c) import receptor (b) Ran GTPase (d) protein translocator 7. Transport of a soluble protein into the lumen of the ER does not require which of the following? (a) protein translocator (b) start transfer sequence (c) stop transfer sequence (d) signal peptidase 8. Transport of a multi-pass transmembrane protein into the ER differs from the transport of a single pass transmembrane protein in which of the following criteria? (a) protein translocator (b) start transfer sequence (c) the location of the start transfer sequence (d) the location of the stop transfer sequence 9. Selection of cargo into transport vesicles requires which of the following proteins or structures? (a) dynamin (b) clathrin coat (c) adaptin (d) cargo receptor

Explanation / Answer

6. The answer is Ran GTPase-Ran GTPase regulates mitosis, nuclear envelope formation, and nucleocytoplasmic trafficking. It is not involved in the process of protein transport for mitochondria.

7. Protein translocator is the answer- It is believed to be responsible for transport of cholesterol and not soluble protein.

8.The answer is start transfer signal sequence- In case of a single pass transmembrane protein transfer: N-terminal signal sequence initiates translocation whereas in case of multi-pass transmembrane protein an internal signal sequence operates as start transfer sequence to initiate translocation.

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