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this enzyme is found in the mitochondrial matrix. It is a massive multi-subunit

ID: 28673 • Letter: T

Question

this enzyme is found in the mitochondrial matrix. It is a massive multi-subunit complex with a MW of 8 X 10^6. It is an important step in the TCA cycle regulation. It is inhibited by ATP, acetyl CoA and NADH. It is alternately regulated by a kinase that deactivates it and a phosphatase that activates it. The reaction it catalyzes is irreversible. The enzyme is ________ ? (there could be more than one answer) A. citrate synthase B. succinate dehydrogenase C. Alpha- ketoglutarate dehydrogenase D. isocitrate dehydrogenase E. pyruvate dehydorgenase F. NADH dehydrogenase G. cytochrome c oxidase

Explanation / Answer

C. Alpha- ketoglutarate dehydrogenase

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