Annie, a thirty-one year old female, is rushed from a local state park to the em
ID: 289201 • Letter: A
Question
Annie, a thirty-one year old female, is rushed from a local state park to the emergency room Her face, limbs and torso are markedly swollen and her skin is covered with numerous wheals. She is having trouble swallowing and her breathing is labored and difficult. She feels faint and a blood pressure determination reveals a systolic/diastolic pressure of 85155 mmHg. Her friends report that she had eaten a large picnic lunch. Hours later in the afternoon, she took a walk through a wildflower garden that was fully in bloom. Half an hour afterwards she was hiking through a wooded area. She wandered off the path and into the forest where she disturbed a asps' nest. After being stung, she ran through a large patch of poison ivy in order to escape from the wasps. Returning quickly to her friends, she rapidly developed symptoms described above and was rushed to the hospital Questions What is the name for this patient's allergic reaction? 2. List all the possible allergens the she encountered at the park What must happen to an allergen in order for it to induce such a reaction (i.e. where must it g once it enters the body)? On the basis of this requirement, which of the allergens you listed is most likely to have induced the reaction? Explain briefly types of allergic responses would you have expected from the other alleraens identified? b. Befo How would they have differed from the reaction observed? re this form of allergic reaction can occur what type of defensive celi has to have previously ncountered the allergen in order to sensitize the individual? hich immune cell responds next in the process of sensitization to the allergen? hat type of immunoglobulin does this cell produce? 7. W 8. Wh at types of cells will then carry this antibody on their membranes in anticipation of a second ow do these cells respond when they encounter the antigen? exposure to the antigen? 9. H What chemical signals do these cells release? 10. H ow does the release of these chemical signals lead to pathological symptoms observed? a. List each of the symptoms and explain how the chemical signals would cause them this response an immediate or delayed hypersensitivity? 11. Is 12. Why would epinephrine be a good treatment for the patient's condition? (i.e. how would epinephrine help to alleviate each of the pathological symptoms?) Explain briefly Lichtenstein, L. Allergy and the Immune System. Sci. Am. 269: 116-24, 1993 rence ten by William H. Clift copyright by Prentice Hall, IncExplanation / Answer
3) The body's immune system involves the white blood cells, which produce antibodies.
Her face, limbs and torso are markedly swollen and her skin is covered with numerous wheals,
She is having trouble swallowing and her breathing is labored and difficult, She feels faint and a
blood pressure determination reveals a systolic/diastolic pressure of 85/55 mmHg.
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