Below are given portions of the sequence for a\"wild type\" mRNA and for several

Question

Below are given portions of the sequence for a"wild type" mRNA and for several additional mRNAs from mutated DNAsequences. Using the table in your book, give the amino acidsequence specified by the wild type mRNA. Then give the amino acidsequence of the mutant.
Wild Type: 5'...A U G C U C U C A A A G G U C G C CU G A G A G ...3'
Mutant A: 5'... A U G C U C C C A A A G G U C G C CU G A G A G ...3'
Mutant B: 5'... A U G C U C U C C A A G G U C G C CU G A G A G ...3'
Mutant C: 5'... A U G C U C U C A U A G G U C G C CU G A G A G ...3'
I am not understanding this things.Pls help.
Wild Type: 5'...A U G C U C U C A A A G G U C G C CU G A G A G ...3'
Mutant A: 5'... A U G C U C C C A A A G G U C G C CU G A G A G ...3'
Mutant B: 5'... A U G C U C U C C A A G G U C G C CU G A G A G ...3'
Mutant C: 5'... A U G C U C U C A U A G G U C G C CU G A G A G ...3'
I am not understanding this things.Pls help.

Explanation / Answer

Wild Type: 5'...            A U G C U C U C A A A G G U C G CC U G A G A G ...3' aminoacids--met-leu-ser-lys-val-ala-stop aminoacids--met-leu-ser-lys-val-ala-stop
Mutant A: 5'... A U G C U C C C A A A G G U C G C C U G A G A G...3'        met--leu-pro--lys-val--ala-stop        met--leu-pro--lys-val--ala-stop
Mutant B: 5'... A U G C U C U C C A A G G U C G C C U G A G A G...3'         met-leu-ser-lys-val-ala-stop         met-leu-ser-lys-val-ala-stop
Mutant C: 5'... A U G C U C U C A U A G G U C G C C U G A G A G...3'        met-leu-ser-stop the wild type and mutant B have the same amino acidcomposition.so it is a silent mutationin mutant B. While the other mutants A,C are nonsensemutations which give rise to a non functional protein. hope this helps

Related Questions

Navigate

• Browse (All)
• Browse B
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.