a. If a father has the defective x chromosome and the mother hasgood XX chromoso

Question

a. If a father has the defective x chromosome and the mother hasgood XX chromosomes, what is the probability that a son willinherit the disease?

b. If a father has the defective x chromosome and the mother asgood XX chromosomes, what is the probability that a daughter willinherit the disease?

c. If a mother has one defective x chromosome and one good Xchromosome, and the father has good XY chromosomes, what is theprobability that a daughter will inherit the disease?

d. If a mother has one defective x chromosome and one good Xchromosome, and the father has good XY chromosomes, what is theprobability that a daughter will inherit the disease?

Explanation / Answer

a) No chance. 0. The x will always be paired withan X and can't be paired with a Y, when following basic Mendeliangenetic boxes (see below)      X     X x   xX     xX   0/2for females Y  XY   XY   0/2 formales b) Again 0. The mother's contributing no x chromosomes,meaning father's defective x will always be paired with astrong X. c) No chance. There is a 1/2 chance a son will bediseased but both daughter's combos host at least one strongX.      x     X X xX   XX   0/2 for females Y xY   XY    1/2 formales d) I assume that either c or d asked for the probability ofson's inheritance and that would be 1/2.

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