A 35-year-old man presents with anemia, neutropenia, thrombocytopenia, myeloblas

Question

A 35-year-old man presents with anemia, neutropenia, thrombocytopenia, myeloblasts with the presence of Auer rods, and one or two distinct nucleoli and promyelocytes. Cytochemistry examination demonstrates peroxidase and Sudan black B (SBB) positive and TdT terminal eoxynucleotidyl transferase (TdT) negative. This hematologic picture is consistent with: A) Acute lymphoblastic leukemia (ALL) Acute myeloblastic leukemia (AML) Chronic myelocytic leukemia (CML) Chronic lymphocytic leukemia (CLL) None of the above B) C) D) E) 8. A 5-year-old girl presents with anemia, neutropenia, thrombocytopenia , lymphoblasts, and prolymphocytes. Cytochemical positive for TdT. This hematologic picture is consistent with: A) ALL B) AML C) CM D) E) examination shows myeloperoxidase and S8B negative, and a CLL None of the above 9. "Pre-leukemia myelodysplastic features in acute myeloid leukemia may include. A) Hypergranular neutrophils B) Hypogranular neutrophils C) D) Monocytoid cells Plasmacytoid cells None of the above E) 10 A strong PAS reaction supports the diagnosis of A) B) C) D) E) Sickle cell anemia Type L3 ALL Pernicious anemia Erythroleukemia None of the above 11. Which of the following cytochemical stains differentiates AML from ALL? A) Myeloperoxidase B) PAS C) Nonspecific esterase All of the above None of the above D) E) presence of Auer rods is abundant The cells react near 100% with Sudan black and peroxidase; however, the reaction is negative for non-specific esterase. Disseminating intravascular coagulation (DIC) is frequently associated with this disorder. What is the FAB classification? A) M1 B) M6 C) M2 D) M3 E) M4 12. This acute leukemia contains primarily abnormal promyelocytes with heavy granulation, and the

Explanation / Answer

10. PAS is the stain which is used for both the dignostic and research purposes. The answer is option (d) None of the above. Because the options given here is full of blood related disease. Here this stain is used only for the daignosis for the glycogen storage diseases, Some tumors and some funga infectons. So the option is (D)

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