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Thousands of SNPs across the genome were analyzed in pooled DNA samples from hum

ID: 303497 • Letter: T

Question

Thousands of SNPs across the genome were analyzed in pooled DNA samples from humans who had been sorted into groups according to their age. For the vast majority of these sites, there was no change in the relative frequencies of different variants as these humans aged. Sometimes, albeit rarely, a particular variant at one position was found to decrease in frequency progressively for people over 50 years old. Which of the possible explanations seems most likely?

A) Those people born more than 50 years ago came from a population that tended to lack the disappearing SNP variant.

B) The nucleotide in that SNP at that position is unstable, and mutates with age.

C) The SNP variant alters an important gene product in a way that shortens the human life-span, so these people are no longer part of the statistics used to calculate frequencies in the aging populations, or is linked to a neighboring allele that has this effect.

E) DNA repair processes are able to recognize the differences and repair them, and the older the people the more likely this is to happen.

A) Those people born more than 50 years ago came from a population that tended to lack the disappearing SNP variant.

Explanation / Answer

The answer is e)

Dna changes and repairs itself over a period time .it's is the human phgsiophys to maintain the balance in the cells and to repair its system.hence the same possibility here has a great chance and over a long time slowly it replicates and at a certain time the gene mutated will be deleted and replaced to the original gene.

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