Researchers characterize a new disorder associated with food allergies in the US

Question

Researchers characterize a new disorder associated with food allergies in the US. The disorder produced by a recessive allele so people exhibiting symptoms must have two copies of the recessive allele. Approximately 1 in 3,000 people in the US. appear afflicted by the disorder (exhibit symptoms). Assuming Hardy-Weinberg equilibrium for this gene, what is the frequency of the recessive allele in the population? (will vary depending on rounding so select the closest answer) ~0.03 ~0.0003 ~0.018 ~0.982 ~0.9997 Researchers characterize a new genetic disorder associated with food allergies in the US. The disorder is produced by a recessive allele so people exhibiting symptoms must have two copies of recessive allele. Approximately 1 in 3,000 people in the appear afflicted by the disorder (exhibit symptoms). Assuming Hardy-Weinberg equilibrium for this gene and a population size of 300'000,000 people in U.S., how many people are carriers of the disease allele but do not efxhibit symptoms heterozygous)? ~3,000 ~99, 990 ~3'000,000 ~10'750,000

Explanation / Answer

Question 10 –

Therefore, by knowing the recessive phenotype and, thereby, the frequency of that recessive allele is :-

1 in 3000 means = 1/3000 = 0.003

q2 (recessive allele) is = 0.003

therefore, q is 0.0003 = 0.0173 i.e. equals to 0.018

The frequency of recessive allele is 18%

similarly, p is 0.982 by formula (p+q=1)

and 2pq = 1.88

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