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In table 2, what complicates the inspection of confounding by comparing crude an

ID: 3128952 • Letter: I

Question

In table 2, what complicates the inspection of confounding by comparing crude and adjusted ORs?

A. The unadjusted OR is given instead of the crude OR.

B. The reference category is in the middle range

C. The Crude OR and the adjusted OR are based on different sample sizes.

D. There are too many levels of each covariate for direct comparison.

TABLE 2 Unadjusted and Adjusted ORs for Asthma in Relation to the Exposure Variables Birth Weight, GA, and Birth Weight SDS, Respectively, in the Cohort Analyses of Swedish Twins Aged 9 or 12 Years Exposure Variable Unadjusted OR (N= 10918) Adjusted OR N- 8119)a Birth weight, g 2.01 (1.70-2.38) 1.09 (0.93-127) 1.00 0.89 (0.75-1.04) 0.91 (0.69-1.19) 1.55 (1.40-1.72) 2.12 (173-2.60) 1.17 (0.98-1.40) 1.00 0.91 (0.75-1.10) 1.07 (0.79-1.45) 1.57 (1.38-1.79) S1999 2000-2499 3000-3499 3500 Birth weight per 1000-g decrease GA, wk 531 32-34 35-36 37-38 39-40 241 2.49 (1.95-3.16) 1.72 (1.42-2.07) 1.26 (1.06-1.49) 1.00 0.92 (0.77-1.10) 1.03 (0.60-1.79) 1.11 (1.08-1.13) 237 (1.78-3.17) 1.70 (1.36-2.14) 1.29 (1.06-1.56) 1.00 0.94 (0.78-1.17) 1.14 (0.47-1.89) 1.10 (1.07-1.13) GA per reduced wk Birth weight SDS Less than -1.0 -1.0to-0.5 -0.5 to 0.5 0.5 to 1.0 1.0 1.17 (0.99-1.37) 0.97 (0.82-1.14) 1.00 0.95 (0.80-1.13) 0.87 (0.73-1.03) 1.09 (1.03-1.16) 1.23 (1.02-1.49) 0.96 (0.78-1.17) 1.00 1.03 (0.85-1.12) 0.96 (0.78-1.18) 1.07 (1.00-1.15) Birth weight SDS per decrease of SD Adjusted for child's gender, age, and zygosity, maternal age and parity, maternal education, smoking during pregnancy family situation, country of birth, and BMI.

Explanation / Answer

what complicates the inspection of confounding by comparing crude and adjusted ORs?

C. The Crude OR and the adjusted OR are based on different sample sizes.

as you can see in the table and data the OR are based from different samples sizes that would be compcated for us

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