(a) Glucose 1. Inhibits phosphofruc- 6-phosphate (b) Low ATP/AMF tokinase in the
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(a) Glucose 1. Inhibits phosphofruc- 6-phosphate (b) Low ATP/AMF tokinase in the liver ratio (c) Citrate (d) Low pH (e) Fructose 2. Glucokinase 3. GLUT2 4. Inhibits hexokinase 5. Inhibits phosphofruc- tokinase in muscle 6. Inhibits phosphofruc- 7. Stimulates pyruvate 8. Stimulates phospho- 9. Causes the insertion of 1,6-bisphosphate (f) Fructose 2,6- tokinase bisphosphate (g) Insulin kinase (h) Has a high KM for (i) Transporter specific to (j) High ATP/AMP fructokinase in the liver glucose liver and pancreas ratio GLUT4 into cell mem branes 10, Stimulates phospho- fructokinaseExplanation / Answer
a-4 it inhibit hexokinase.
b-10 it increases activity of phosphofructokinase.
c-6 it inhibited by citrate. if citrate is build up it means glycolysis can slow down and no need of more fuel.
d-5 pH falls when muscle functioning is anaerobically .
e-7 it increases the activity of pyruvate kinase.
f-8 it activate the phosphofructokinase.
h-2 high Km and glucokinase work together.
j-1high ATP inhibit phosphofructokinase.
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