Arabidopsis thaliana Populus trichocarpa 100 20 Oryza sativa 100 1 12 20 Apis me

Question

Arabidopsis thaliana Populus trichocarpa 100 20 Oryza sativa 100 1 12 20 Apis mellifera Ciona intestinalis 2.5 30 20 10 1.5 Danio rerio Mus musculus 100 100 70 70 50 upstream repeat downstream upstream repeat downstream The problem is to explain why the methylation rate is higher in 7 of the 8 data sets for genomic regions containing repeats than in genomic regions immediately upstream or downstream from the repeats. (The honey bee shows the reverse pattern, for reasons we don't understand yet, and while it doesn't look like there is a real rise in the mouse, there is actually a slight but statistically significant rise in methylation rate) The increase in the rate of methylation is because A. methylation is used by mobile elements to increase their rate of transposition. B. methylation is used by the host cells to inhibit transcription of harmful mobile elements C. methylation is used by the host cells to increase transcription of harmful mobile elements D. methylation is used by the host cells to inhibit transcription of restriction endonucleases that cut harmful mobile elements E. methylation always increases near centromeres

Explanation / Answer

methylation is used by the host cells to inhibibt the transcription of harmful mobile elements. In case of hypomethylation at these mobile elements, these are expressed and are inserted randomly in the genome creating genetic abnormalities

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