Need assistance with this 6. A study is conducted in patients with HIV. The prim

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Need assistance with this

6. A study is conducted in patients with HIV. The primary outcome CD4 cell count, which is a mea sure of the stage of the disease. Lower CD4 counts are associated with more advanced disease. The in- vestigators are interested in the association between vitamin and mineral supplements and CD4 count. A multiple regression analysis is performed relating CD4 count to the use of supplements (coded as l yes and 0 no) and to the duration of HIV in years (i.e., the number of years between the diagno- sis of HIV and the study date). For the analysis, CD4 count 30.23(Duration of HIV

Explanation / Answer

Given equation,

y = 501.41 + 12.67(Supplements) - 30.23(Duration of HIV)

a) For supplements = 1, Duration of HIV = 2.5

CD4 count (y) = 501.41 + 12.67(1) - 30.23(2.5)

CD4 count = 438.505 = 439 (Approx)

b) For supplements = 0, Duration of HIV = 0 (Since the patient was diagnosed with HIV at study enrollment only)

CD4 count (y) = 501.41 + 12.67(0) - 30.23(0)

CD4 count = 501.41 = 501 (Approx)

c) For supplements = 0, Duration of HIV = 2.5

CD4 count (y) = 501.41 + 12.67(0) - 30.23(2.5)

CD4 count = 425.835 = 426 (Approx)

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