8) Proteins A and B bind to one another through the interface shown in the diagr

Question

8) Proteins A and B bind to one another through the interface shown in the diagram below. Place each of the following amino acids at all positions in Protein B (1', 2', 3', 4') where the R-group of the amino acid might contribute positively to the binding interaction between these two proteins. AMINO ACIDS LIST: Ser, Gin, Lys, Leu, Pro Amino acids that would fit at position 1': _ Amino acids that would fit at position 2': _ Amino acids that would fit at position 3': _ Amino acids that would fit at position 4': _

Explanation / Answer

1) ser

2) ser

3) Gln

4) lys

because the amino acids which are hydrophilic are only present in interface of two proteins

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