What is the method of localization of 18FDG in malignant tumors? Metabolic trapp

Question

What is the method of localization of 18FDG in malignant tumors? Metabolic trapping Receptor binding Simple diffusion All of the above Patient radiation exposure from PET radiopharmaceuticals during imaging procedures is: Higher than those of other nuclear medicine procedures Lower than those of other nuclear medicine procedures Comparable to those of other nuclear medicine procedures At the present time, it is unknown One major factor expanding clinical PET has been: The possibility of correcting photon attenuation The development of new scintillator detectors other than BGO The use of PET in renal diseases The development and availability of 18FDG

Explanation / Answer

Answer 9:- Option A metabolic traping

Explanation :-The 18FDG (fluorodeoxyglucose) is an analog of glucose that when delivered within the melignant tumors is phosphorylated by hexokinase that gets traped within cells due to charge on 18DFG that then undergoes glycolysis.

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