More choices of transition rate matrices are available. Choose one more that is

Question

More choices of transition rate matrices are available. Choose one more that is different from the above three. Among these four matrices, which one is more appealing to you in terms of usefulness. Explain your choice. More choices of transition rate matrices are available. Choose one more that is different from the above three. Among these four matrices, which one is more appealing to you in terms of usefulness. Explain your choice. i. Jukes-Cantor model (1969): 3r 3r c r r 3r 3r. In the above matrix the parameter, r 0, denotes the rate (transition rate) at which one type of nucleotide changes to another. ii. Kimura model (1980) a /-(r 2s) r -(r 2s iii. Felsenstein model (1981) a /-a(1 -pa) apa apt ape g apa -a (1 -pa) apc apg -a (1 -pe) apt apa t apa. ape -a(1 -pe) apg

Explanation / Answer

Second one that is Kimura model is more different from the other two because, both first one that is Jukes cantor model and felsentien model consist single element apart from the diagonal elements, where as Kimutra model consist of two distinguished element r and s apart from diagonal element.

Therefore we will choose 2nd matrix based on Kimura model

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