You are a young researcher at the National Institute Health. You are very intere
ID: 32736 • Letter: Y
Question
You are a young researcher at the National Institute Health. You are very interested in a new drug that has the potential to decrease blood cholesterol by inhibiting the enzyme in liver cells that is the key step in making LDLs.
Of the following model system, which would you find useful in your studies and which ones would not be useful. For those you find useful describe in a few words what kind of studies can be accomplished? Explain your answer.
a)E. coli
b)Yeast
c)Drosophila
d)Mouse
e)C. elegans
f)Cell Culture
Explanation / Answer
Low density lipids (LDL) are synthesized in the liver by the liver enzymes. As a young researcher interested in studying the effect of a new drug in lowering LDL, I would choose a mouse as my experimental animal.
The reason for selecting a mouse is
In order to establish the effeciency of the drug, blood cholesterol levels in blood are analyzed using several ready to use cholesterol assay kits.
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