A true-breeding black mouse is crossed with an albino mouse, producing F1 offspr

Question

A true-breeding black mouse is crossed with an albino mouse, producing F1 offspring that are all agouti (grizzled fur).The F1s are intercrossed, producing F2s with the following phenotypes:48 agouti, 28 albino, and 18 black.Actual research has revealed that fur color in this population of mice is controlled by two genes.

A. What is the observed phenotypic ratio for the F2 generation?

B. The researchers believe that dominant epistasis is occurring in this cross.Use the chi test to test their hypothesis.Are they correct?

C. Do you think another type of epistasis is occurring?Test your hypothesis with another chi square.Are you correct?

Explanation / Answer

A) Phenotypic ratio: Agouti [48/94] : Albino [28/94] : Black [18/94]

B) No this is theyare not correct because here it is recessive allele (b) of one gene masking the effect of dominant allele (A) of other gene.

C) Yes here we have RECESSIVE EPISTASIS.

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