essentials of bios period. The data are summarized below velopment or atnal fibr
ID: 3356688 • Letter: E
Question
essentials of bios period. The data are summarized below velopment or atnal fibrillation was monitored over a 10-yea Developed AF Did not Develop AF 120 Men Women 86 6453 7074 a) Compute the cumulative incidence of AF in men and in women. b) Compute the relative risk of AF incidence comparing men to women. c) Compute the odds ratio of AF incidence comparing men and women. A clinical trial designed to show the efficacy of a new drug in reducing progression to hypertension reports the following: New Drug Placebo 200 Sample size Progressionto hypertension | 14% 200 19% Compute the relative risk of progression to hypertension among patients receiving the new drug as compared to the placebo a) Compute the difference in proportions of patients progressing to hypertension between the two groups. b)Explanation / Answer
(i) Cumulative Incidence of AF in men and women = 120 + 86 / (6453 + 7074 + 120 +86) = 206 / 13733 = 0.01500
= people who developed disease / total people at risk of disease
(ii) Relative risk of AF incidence comparing men to women
= P( men getting disease) / P( women getting disease)
=( 120 / (120 +6453) ) / (86 / (86+7074)) = (120 / 6573) / (86/ 7160) = 0.0182 / 0.0120 = 1.5166
(iii) Odds Ratio of AF incidence comparing men to women
= Odds of men getting disease / Odds of women getting disease = (120 / 6453) / (86 / 7074)
= 0.018596 / 0.01215
= 1.5305
Related Questions
Navigate
Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.