Consider a population with the following genotypic frequncies: 0.1296 TT + 0.460

Question

Consider a population with the following genotypic frequncies: 0.1296 TT + 0.4608 Tt + 0.4096 tt (*** I have answers to A and B, but I am unsure of whether they are correct or not. )

a) Give the allele frequences for alleles T and t (5 decimal places).

I got T = 0.36, and t = 0.64

b) Assume that the fitness of the homozygous recessive trait is 0.7, and it is completely recessive. Compute the allele freq. of T for the next generation.

I got T = 0.3

C) Go back to the originial popluation (part a). Assume there is migration from a population with genotypic frequencies 0.49 TT + 0.42 Tt + 0.09 tt. Five percent of the individuals who breed on the island are immigrants. Compute the allele frequences for T for the next generation.

D) Go back to the original population (part a). Assume there is mutation. The mutation rate from T to t is 3x10^-3 and from t to T is 2x10^-4. COmpute the allele frequency for T for the next generation (no rounding).

e) give the genotypic frequencies if this population (part a) is inbred until F= 0.45

THANK YOU SO MUCH!

Explanation / Answer

Answer.

Given Genotypic frequncies: 0.1296 TT + 0.4608 Tt + 0.4096 tt

a) Give the allele frequences for alleles T and t

Now for
Allele "T" = sq. root of TT
= sq. root of 0.1296
   = 0.36

Allele "t" = sq. root of tt
= sq. root of 0.4096
   = 0.64

b) Assume that the fitness of the homozygous recessive trait is 0.7, and it is completely recessive. Compute the allele freq. of T for the next generation.

p + q = 1
if q = 0.7 (for Recessive Allele)
Then,
p = 1- q (for Dominant Allele)
p = 1- 0.7
p = 0.3 i.e T = 0.3

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