statistics problem, show all work please, will rate Placebo effect in Parkinson\

Question

statistics problem, show all work please, will rate Placebo effect in Parkinson's disease patients. The placebo effect occurs when a patient experiences a perceived benefit after receiving an inert substance. To help understand the mechanism behind this phenomenon in Parkinson's disease patients, investigators measured striatal RAC binding at a key point in the brains in six subjects. RAC binding was reduced by an average of 0.326 units on a placebo in the six subjects (s_d = 0.181).^1 Test this difference for statistical significance.

Explanation / Answer

As

t = d*sqrt(n) / sd

Then

t = (-0.326)*sqrt(6) / 0.181 = -4.411788156

As for 0.05 significance, df = n - 1 = 5,

tcrit = -2.015048373

Then, as t < -2.015, then we conclude that the difference in RAC binding is significant at 0.05 level.

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