Response optimization is used to determine the optimal conditions for recovery o
ID: 3383598 • Letter: R
Question
Response optimization is used to determine the optimal conditions for recovery of a sample for HPLC. The three factors are: A- Solvent (Hexane or Ethyl Acetate); B- pH (8 or 10); and C- time (30 or 60 minutes). The two response variables are Recovery and Variance. What are the optimal conditions for this process?
Run
Recovery
Variance
(1)
65.3
4.5
a
81.3
4.8
b
53.3
3.7
ab
69.9
5.5
c
61.8
3.7
ac
77.45
6.9
bc
73.9
3.6
abc
89.9
6.2
Run
Recovery
Variance
(1)
65.3
4.5
a
81.3
4.8
b
53.3
3.7
ab
69.9
5.5
c
61.8
3.7
ac
77.45
6.9
bc
73.9
3.6
abc
89.9
6.2
Explanation / Answer
What are the optimal conditions for this process?
recovery of 65.3 and variance 4.5
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