10. Using the cAMP pathway, which of the following would be the result of a depl
ID: 3473810 • Letter: 1
Question
10.
Using the cAMP pathway, which of the following would be the result of a depletion in intracellular ATP?
A)
Decreased G-protein activity
B)
Increased production of AMP
C)
Decreased phosphorylation of intracellular proteins
D)
Increased activity of adenylate cyclase
E)
Increased activity of phosphoprotein phosphatase
10.
Using the cAMP pathway, which of the following would be the result of a depletion in intracellular ATP?
A)
Decreased G-protein activity
B)
Increased production of AMP
C)
Decreased phosphorylation of intracellular proteins
D)
Increased activity of adenylate cyclase
E)
Increased activity of phosphoprotein phosphatase
Explanation / Answer
Answer will be C) decreased phosphrylation of intracellular proteins. This is because cAPM produced by conversion of ATP , results in activation of protien kinase which further phosphorylates other proteins
A) is not - as G protein activity may be through IP3- DAG, pathway or direct ion channel
B) is not -increase production of AMP is due to action of PDE on cAMP, in case of a large amount of ATP gets converted into cAMP, but this is not the case here
D) is not- this occur if ATP present in large amount
E) is not-for-profit reason same as D
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