Review the hemostatic mechanisms that lead to the formation of a platelet plug b

Question

Review the hemostatic mechanisms that lead to the formation of a platelet plug by completing each sentence below. platelet activation underlying connective tissue fibers. nitric oxide adhere to exposed collagen in a damaged vessel and release contents of their secretory vesicles. fibrinogen The secreted substances help cause and aggregation. secreted by These two processes are also enhanced by endothelial cells, and by , collagen produced by the platelets platelet plug As platelets aggregate, forms the bridges between them. thromboxane A2 The resulting can completely seal small breaks in blood vessel walls. von Willebrand factor The platelet plug does not spread along normal endothelium because the latter secretes prostacyclin and , both of which inhibit platelet aggregation Platelets

Explanation / Answer

1. Collagen.

2. Platelets.

3. Platelet activation.

4.Thromboxane A2, Von Willebrand factor.

5. Fibrinogen.

6. Platelet plug.

7. Nitric oxide.

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