Describe the hormonal mechanism of regulation of blood pressure through the kidn

Question

Describe the hormonal mechanism of regulation of blood pressure through the kidney. What are the mechanisms to rise systemic blood pressure? 1. Describe what the stimulus to release renin and name the cells that preform this activity 2. Describe the conversion of renin into angiotensin II Describe the hormonal mechanism of regulation of blood pressure through the kidney. What are the mechanisms to rise systemic blood pressure? 1. Describe what the stimulus to release renin and name the cells that preform this activity 2. Describe the conversion of renin into angiotensin II What are the mechanisms to rise systemic blood pressure? 1. Describe what the stimulus to release renin and name the cells that preform this activity 2. Describe the conversion of renin into angiotensin II

Explanation / Answer

Kidneys regulate blood pressure by changing blood volume. When the blood pressure is low, the juxtaglomerular cells in the kidneys secrete renin into the blood. Renin converts the plasma protein angiotensinogen to angiotensin I. This in turn is converted to angiotensin II by angiotensin converting enzyme from the lungs. Angiotensin II stimulates adrenal cortex to secrete aldosterone. Aldosterone retains water and sodium by increasing their tubular reabsorption.

1) Renin is secreted by the granular cells of juxtaglomerular apparatus. Renin is secreted in response to decreased renal perfusion pressure, signals from the macula densa and beta adrenergic stimulation.

2) Renin converts the plasma protein angiotensinogen to angiotensin I. This in turn is converted to angiotensin II by angiotensin converting enzyme from the lungs.

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