A previously normal patient develops a buidup of plaque that severely reduces th

Question

A previously normal patient develops a buidup of plaque that severely reduces the blood flow to his right kidney. Click on all of the physiological changes that would be expected after the blockage compared to what they were before. Decreased mean arterial blood pressure Decreased plasma angiotensin Il concentration Increased plasma angiotensin II concentration Decreased renin release from the right kidney Increased renin release from the right kidney Increased plasma aldosterone concentration Decreased plasma aldosterone concentration Decreased plasma renin concentration Increased plasma renin concentration Increased mean arterial blood pressure Increased renin release from the left kidney Decreased renin release from the left kidney

Explanation / Answer

When a decreased blood flwo to the kidney happens, subsequently increases the blood pressure of that area Renin angiotensin aldosterone system is a hormone system used to maintain the blood pressure and fluid balance in the body, so when an increased pressure un the right kidney leads to an increased concentration of these hormone in the blood When the renal blood flow is reduced the juxtaglomerular apparatus of kidney converts the precursor prorenin into renin and increased plasma renin concentration occurs (The renin is released from left kidney increases) The renin then converts angiotensinogen which is released from liver to angiotensin, The angiotensin1 is converted to angiotensin 2 by angiotensin converting enzyme. So an increased concentration of plasma angiotensin2 Angiotensin2 releases the aldosterone from adrenal cortex and this hormone causes the reabsorption of sodium and water inorder to increase the extra cellular fluid so BP increases, hence an increased concentration of plasma aldosterone occurs The above mechanisms are occurs when the BP is low, but when the RAS became abnormal the BP becomes too high Overall the mean arterial pressure increases after the blockage of blood flow to the kidney happens

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