The peptide hormones secreted by the anterior lobe of the pituitary gland are or

Question

The peptide hormones secreted by the anterior lobe of the pituitary gland are organized into three "families": the TSH-FSH-LH family, the ACTH family, and the GH-prolactin family. Within each hormone family the "family members" are described as structurally and functionally homologous What does homology among hormones (ligands) likely suggest with regard to their respective hormone receptors? A. B. Describe one way in which researchers can use knowledge of hormone and receptor homology to help determine the properties/mechanisms of newly discovered proteins/peptides that have homology to previously characterized proteins.

Explanation / Answer

A.Family of hormones always share a common structure/ amino acid sequence which is called as conserved domain. Hormones can bind to the receptors of their family.

B. If any peptide resmbles homology of a particular hormone, then that peptide can bind the receptor of the hormone. It can be used to manipulate hormonal action. And also its effect on hormonal receptors can be studied whether it is augmenting or antagonizing.

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