Your patient is observed to have symptoms that are consistent with elevated conc

Question

Your patient is observed to have symptoms that are consistent with elevated concentrations of epinephrine in the blood, including a rapid heart rate, anxiety, and elevated fatty acid concentrations. However, the circulating epinephrine concentrations are tested and found to be in the normal range. Click on the statement below that offers the best explanation for your patient's condition. Since estrogen is permissive of the actions of epinephrine, your patient may have a hypersecreting ovarian tumor This leads to elevated circulating concentration of estrogen and a greater potentiation of the actions of epinephrine on the heart, nervous system, and adipose tissue Since cortisol is permissive of the actions of epinephrine, your patient may have a tumor within the adrenal cortex. This leads to elevated circulating concentration of cortisol and a greater potentiation of the actions of epinephrine on the heart, nervous system, and adipose tissue. Since thyroid hormone is permissive of the actions of epinephrine, your patient may have thyroid disease. This leads to elevated circulating concentration of thyroid hormone and a greater potentiation of the actions of epinephrine on the heart, nervous system, and adipose tissue Since growth hormone is permissive of the actions of epinephrine, your patient may have anterior pituitary disease. This leads to elevated circulating concentration of growth hormone and a greater potentiation of the actions of epinephrine on the heart, nervous system, and adipose tissue

Explanation / Answer

Thyroid hormone is permissive to actions of epinephrine.thyroid hormone stimulates the synthesis of receptors for epinephrine on its target cells.For example adipose tissue, where permissive levels of thyroid are needed for epinephrine to release fats from the adipose tissue. TH up-regulates beta-adrenergic receptors in many tissues, particularly in the heart and nervous system. thus the symptoms of excess thyroid hormone concentration closely resemble some of the symptoms of excess epinephrine-like rapid heart rate and anxiety.

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