please answer these questions 1. Transport of glucose across the basolateral sur
ID: 3482984 • Letter: P
Question
please answer these questions
1. Transport of glucose across the basolateral surface of the intestinal epithelial cell is accomplished by
A. Primary active transport
B. Secondary active transport
C. Facilitated diffusion
D. Simple diffusion
2. Great aunt just had a small bowel resection performed. This is a surgery that removes part of the small intestine. Which would be the most likely side effect?
a. vomiting
b. constipation
c. diarrhea
3. One treatment goal for Type II Diabetes is to lower blood glucose levels. Would a drug that inhibits glucagon be an effective choice?
a. Yes
b. No
Explanation / Answer
1. Transport of glucose from the intestinal lumen into blood is a two-step process. First, the import of glucose from intestinal lumen into the intestinal epithelial cells is carried out against concentration gradient. Thus, the process is facilitated via the Na+/ Glucose symport and activity of Na+/K+ ATPase pump. However, the movement of glucose across the basolateral surface of the intestinal epithelial cells is along the concentration gradient. But, since, glucose is a large molecule, it cannot passively diffuse out of the cell. This process is facilitated by the GLUT2 transporter protein, which is located near the basolateral surface of the intestinal epithelial cells.
Thus, the answer to this question is: C. Facilitated Diffusion.
2. Small intestine is majorly responsible for digestion and absorption of ingested fluids and nutrients. The resection of a part or whole of small intestine may likely cause these functions to be hampered. A patient may suffer from different complications based on the section of small intestine that has been surgically removed. However, the most likely side-effect is Dairrhoea (since, the absorption of fluids doesnot take place).
The answer is: C. Diarrhea.
3. Glucagon is the hormone responsible for increasing blood glucose levels. The hormone acts by causing release of glucose from liver. So, if a drug inhibits the glucagon, it will result in lower blood glucose levels.
Thus, the answer for this question is: A. Yes.
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